Charming Vacation Rentals in Charleston, MO

Travel Inn and Suites- Sikeston Miner I-55 exit-67
Hotel
100 Matthews Lane, Sikeston, MO, MO 63801

Travel Inn and Suites- Sikeston Miner I-55 exit-67 is offering accommodations in Sikeston. With free WiFi, this 4-star motel offers room service and a 24-hour front desk. At the motel, every room includes a desk and a flat-screen TV. All guest rooms will provide guests with a fridge. Cape Girardeau Regional Airport is 27 miles away.

Guest Reviews:

- "Was just wonderful after a days drive." - "Awesome stay for an awesome value" - "Excellent cost for what you get!!" - "Nice, place, comfy beds, friendly staff" - "Was just fine." - "Staff was really nice. We was clean rooms to clean." - "Nice clean place with good breakfast, would stay again!" - "Father's Day in Sikeston" - "Great value for the money!" - "Nice, I would stay again" - "Surprise Surprise"

Drury Inn & Suites Sikeston, MO
Hotel
2608 East Malone Ave, Miner, Sikeston, MO, 63801, USA

Hotel in Sikeston with free breakfast and a fitness center
Along with an indoor pool, this smoke-free hotel has an outdoor pool and a fitness center. Free buffet breakfast is provided, as well as free WiFi in public areas, free self parking, and a free manager's reception. Additionally, coffee/tea in a common area, a business center, and dry cleaning are onsite.
Drury Inn & Suites Sikeston, MO offers 154 accommodations with coffee/tea makers and hair dryers. LCD televisions come with cable channels. Guests can make use of the in-room refrigerators and microwaves. Bathrooms include shower/tub combinations and complimentary toiletries.

This Sikeston hotel provides complimentary wireless Internet access. Business-friendly amenities include desks and phones; local and long-distance calls are complimentary (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Housekeeping is provided daily.


An indoor pool and an outdoor pool are on site. Other recreational amenities include a fitness center.

Guest Reviews:

- "Staying at a Drury is always good ... they all maintain a high standard" - "My new favorite hotel. Price was very reasonable, room was comfortable and clean. They have a happy hour from 5:30 to 7 with several selections and included 3 drinks. Breakfast was also very good and all included in the price" - "Very friendly staff. Very clean and comfy. We really enjoyed our stay!" - "Nice and clean hotel" - "If traveling, one of the best stops for rest "

Drury Inn & Suites Sikeston
Hotel
2608 East Malone Avenue, Sikeston, MO, MO 63801, USA

Just off Interstate 55 and less than 3 miles from downtown Sikeston and Sikeston Depot, this Missouri hotel features a complimentary hot breakfast each morning. A modern fitness center is available on site. A microwave and a refrigerator are included in all rooms at the Drury Inn & Suites Sikeston. Free toiletries and ironing facilities are also provided in each guest room. Guests can enjoy a swim in the indoor-outdoor pool or relax in the hot tub at Drury Inn & Suites Sikeston. A laundromat and a 24-hour business center are also featured on site. Free snacks and beverages are served nightly. The Bootheel Golf Club is 3 miles from this hotel. Sikeston Factory Outlet Stores are less than a 2-minute drive away.

Guest Reviews:

- "wonderful , peaceful" - "Enjoyable" - "It was a nice relaxing stay, I just don’t think I will get another one on the weekends !" - "MINOR DEFECTS" - "I enjoyed my stay. Will book this Hotel again" - "I would definitely stay here again." - "Nice but not worth $288 for a night!"

Best Western Plus Sikeston
Hotel
120 S Interstate Drive, Sikeston, MO, 63801, USA

Hotel in Sikeston with free breakfast and a fitness center
This smoke-free hotel features an indoor pool, a fitness center, and a 24-hour business center. Free full breakfast, free WiFi in public areas, and free self parking are also provided. Other amenities include a business center, laundry facilities, and a 24-hour front desk.
Best Western Plus Sikeston offers 55 air-conditioned accommodations with MP3 docking stations and coffee/tea makers. 42-inch LCD televisions come with premium cable channels.

Bathrooms include bathtubs or showers, complimentary toiletries, and hair dryers. In-room wireless Internet access (speed: 25+ Mbps) is available for a surcharge. Housekeeping is provided daily.


Recreational amenities at the hotel include an indoor pool and a fitness center.

Guest Reviews:

- "Clean, great breakfast, friendly staff, parking area well lit, accommodations exactly what we wanted. Who could ask for more. Totally recommend and price was great. Easy to book through Expedia. " - "We enjoyed it with no issues" - "The suite was absolutely amazing. It was very roomy, the bathroom was huge and it was at end of hallway where only had 1 neighbor which is great especially when traveling with kids. The king bed and pull out bed were super comfy. Only issue we had was the water pressure wasnt the greatest."

Best Western Plus Sikeston
Hotel
120 South Interstate Drive, Sikeston, MO, MO 63801, USA

Best Western Plus Sikeston is offering accommodations in Sikeston. This 3-star hotel offers a 24-hour front desk and free WiFi. The hotel has an indoor pool, fitness center and a shared lounge. All guest rooms come with air conditioning, a flat-screen TV with cable channels, a fridge, a coffee machine, a shower, free toiletries and a desk. Rooms are complete with a private bathroom equipped with a hairdryer, while some rooms at the hotel also feature a seating area. All rooms feature a closet. The breakfast offers buffet, à la carte or continental options. Cape Girardeau Regional Airport is 27 miles from the property.

Guest Reviews:

- "Good stay!" - "Great hotel room and Great breakfast" - "Clean, safe, comfortable, convenient and affordable place to stay, while attending the Rodeo!" - "Friendly staff" - "Great Breakfast after a great comfy night sleep" - "After a tired day of driving, I found a great hotel with friendly staff and clean comfortable room!" - "overall was good and very clean" - "It was okay until we got to the breakfast and that was not what we were led to believe it would be."

Pear Tree Inn Sikeston
Hotel
2602 E Malone Avenue, Sikeston, MO, 63801, USA

Hotel in Sikeston with free breakfast and a fitness center
An indoor pool, an outdoor pool, and a fitness center are available at this hotel. Free breakfast, free WiFi in public areas, and a free manager's reception are also provided. Other amenities include a hot tub, coffee/tea in a common area, and a business center.
Pear Tree Inn Sikeston offers 80 accommodations with coffee/tea makers and hair dryers. 32-inch LCD televisions come with cable channels. Guests can make use of the in-room refrigerators and microwaves. Bathrooms include shower/tub combinations and complimentary toiletries.

This Sikeston hotel provides complimentary wireless Internet access. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Housekeeping is offered daily and hair dryers can be requested.


An indoor pool, an outdoor pool, and a hot tub are on site. Other recreational amenities include a fitness center.

Guest Reviews:

- "Very clean and friendly." - "Room was very nice. Price reasonable. Could have had evening drinks but did not participate. Breakfast was great; Staff very friendly and helpful." - "Extremely friendly staff, restaurants within walking distance, free deinks and snacks" - "It was very clean and had a really good breakfast!!" - "I enjoy my stay very much the staff was friendly and professional. The room was clean and the beds were comfortable. I did not care for the continental breakfast not much of a variety."

Comfort Inn & Suites Sikeston I-55
Hotel
109 Matthews Lane, Sikeston, MO, MO 63801, USA

Comfort Inn & Suites Sikeston I-55 is a 3-star property located in Sikeston. The hotel provides both free WiFi and free private parking. An American breakfast is available every morning at the hotel. Cape Girardeau Regional Airport is 27 miles away.

Guest Reviews:

- "Good people work here. They help you!" - "The stay was nice will stay there again" - "Great stop on a road trip." - "Clean and comfortable" - "IT WAS OK" - "Not having WiFi in this day and age was a big problem. The room was comfortable and the staff were pleasan"

Days Inn and Suites by Wyndham Sikeston
Hotel
220 S Interstate Dr, Sikeston, MO, 63801, USA

Colonial hotel with free breakfast and a fitness center
Along with a fitness center, this smoke-free hotel has laundry facilities and a 24-hour front desk. Free on-the-go breakfast, free WiFi in public areas, and free self parking are also provided. Additionally, a library, a banquet hall, and a vending machine are onsite.
Housekeeping is available on request.
Days Inn and Suites by Wyndham Sikeston offers 60 air-conditioned accommodations with hair dryers and irons/ironing boards. Satellite television is provided. Refrigerators and microwaves are provided. Bathrooms include bathtubs and complimentary toiletries.

This Sikeston hotel provides complimentary wireless Internet access. Business-friendly amenities include desks and desk chairs, as well as phones; free local calls are provided (restrictions may apply). Housekeeping is provided on request.


Recreational amenities at the hotel include a fitness center.

Guest Reviews:

- "I was continue to use this hotel for my visits because the staff is amazing!!! Ty!!!" - "It was great. Staff was friendly. Breakfast was pretty great too. Very nice and quiet place to stay ☺️☺️" - "Excellent room at a great price! The ice machine was broken due to a power glitch that morning but bed was comfortable and very clean. Will stay again when we travel thru. " - "We stayed the day before the 2024 solar eclipse. Sikeston MO was one of the locations where it was going to be 100% totality. Even though our check out time was 11 AM, the owner allowed any one to stay on the parking lot, or in the next door field where we could all view the historic event. Not all hotel owners would have allowed us to do that. Most gracious. The hotel is in the process of renovation. We had rented a suite. The sleeping room was newly painted and appointed. We like the fact there was no rug, a new floor was laid out. I can see this location is putting in some effort to bring it up to better standards than some Days Inn we have stayed at. It's safe, clean and, again, the owner will go out of his way...what a nice surprise for a change. "

Super 8 by Wyndham Sikeston/Miner Area
Hotel
2609 East Malone Avenue, Sikeston, MO, MO 63801, USA

Super 8 by Wyndham Sikeston/Miner Area is offering accommodations in Sikeston. With free WiFi, this 3-star hotel offers room service and a 24-hour front desk. The hotel features family rooms. All guest rooms features air conditioning, a fridge, a microwave, a coffee machine, a shower, a hairdryer and a desk. Complete with a private bathroom, the rooms at the hotel are equipped with a TV, and some rooms here will provide you with a seating area. Guests at Super 8 by Wyndham Sikeston/Miner Area can enjoy a continental breakfast. Cape Girardeau Regional Airport is 27 miles away.

Guest Reviews:

- "Wonderful hotel with McDonald’s next door" - "NA" - "Atleast i know where not to stay!"

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Hotel
100 Matthews Lane, Sikeston, MO, 63801, USA

Hotel in Sikeston with free breakfast and a 24-hour front desk
Coffee/tea in a common area, a 24-hour front desk, and free breakfast are available at this hotel. Free WiFi in public areas and free self parking are also provided. Other amenities include a vending machine.
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) offers 40 air-conditioned accommodations with complimentary toiletries and blackout drapes/curtains. Each accommodation is individually furnished and decorated. Cable television is provided. Rooms have partially open bathrooms. Bathrooms include shower/tub combinations.

This Sikeston hotel provides complimentary wireless Internet access, with a speed of 100+ Mbps (good for 1–2 people or up to 6 devices). Business-friendly amenities include desks and desk chairs, as well as phones; free local calls are provided (restrictions may apply). Housekeeping is offered daily and irons/ironing boards can be requested.

Guest Reviews:

- "Wonderful little gem in this small town! Very affordable, extremely clean, friendly staff, overall great service. We would definitely stay here again!" - "Accomodations were fine" - "Friendly staff. Comfortable bed. " - "Great rooms,wonderful folks,close to all necessary places " - "Very nice motel. The young lady at check in was very friendly and professional. Needs more visibility, was kinda hard to find." - "Convenience "

Pear Tree Inn Sikeston
Hotel
2602 East Malone Avenue, Sikeston, MO, MO 63801, USA

Offering free Wi-Fi and a cable TV in every guest room, this hotel is less than 3 miles from Sikeston city center and the Sikeston Depot. A complimentary hot breakfast is served each morning. Tea-making facilities are included in all rooms at Pear Tree Inn Sikeston. Free toiletries and ironing facilities are also provided in each guest room. Guests can enjoy a swim in the indoor/outdoor pool or relax in the hot tub at Sikeston Pear Tree Inn. Laundry facilities and a 24-hour business center are also featured on site. A fitness center is also available to all guests. Just off Interstate 55, this hotel is 3 miles from the Bootheel Golf Club. The Sikeston Factory Outlet Stores are less than 5 minutes’ drive away.

Guest Reviews:

- "Very in joyful" - "Probably best motel that I have stayed in lately!!!" - "Excellent experience!!" - "Great but next time I’d get separate beds" - "I will look for other Pear Tree Inns on my trip but was told there are only 8" - "It was Great" - "Great Place to Stay !" - "We would definitely come back." - "Clean comfortable room. Enjoyed our stay." - "It was short and sweet" - "It was fine. Drury hotel next to this one was cleaner"

Super 8 by Wyndham Charleston/Sikeston East MO
Hotel
310 S Story St, Charleston, MO, 63834, USA

Motel in Charleston with free breakfast and a 24-hour front desk
A business center, dry cleaning, and laundry facilities are available at this motel. Free on-the-go breakfast, free WiFi in public areas, and free self parking are also provided. Other amenities include a 24-hour front desk, a computer station, and a TV in a common area.
Super 8 by Wyndham Charleston/Sikeston East MO offers 60 air-conditioned accommodations with hair dryers and blackout drapes/curtains. LCD televisions come with premium cable channels and pay movies. Refrigerators and microwaves are provided. Rooms have partially open bathrooms. Bathrooms include shower/tub combinations.

This Charleston motel provides complimentary wireless Internet access. Business-friendly amenities include phones along with free local calls (restrictions may apply). Housekeeping is provided daily.

Guest Reviews:

- "This property is excellent for the price. My vehicle broke down and this hotel was in walking distance of everything we needed. Great value when you need to find a place fast. My room was clean and staff was friendly. " - "Bed was comfy. They need to fix the popcorn ceiling that is falling off. " - "Comfortable " - "This motel has a humble appearance, but is sufficient. I like the rooms with an inside and outside entrance. All of the rooms are very large. All the staff were helpful. I usually leave too early for the breakfast, but it is enough. I enjoy some hot oatmeal and they have juice, milk, and coffee. "

Days Inn and Suites by Wyndham Sikeston
Hotel
220 South Interstate Dr, Sikeston, MO, 63801, USA

Days Inn and Suites by Wyndham Sikeston is offering accommodations in Sikeston. This 2-star hotel offers luggage storage space. The hotel has a fitness center, a 24-hour front desk and free WiFi throughout the property. At the hotel the rooms have air conditioning, a desk, a flat-screen TV, a private bathroom, bed linen, towels and a patio with a pool view. All rooms will provide guests with a closet and a coffee machine. Guests at Days Inn and Suites by Wyndham Sikeston can enjoy a continental breakfast. Cape Girardeau Regional Airport is 27 miles from the property.

Guest Reviews:

- "The hotel stay was wonderful" - "Nice place and will stay again." - "It was worth the money very quiet and clean" - "Will come back again" - "Room was much larger than we anticipated and beds were comfortable. Enjoyed our stay." - "Was not happy that we had to pay double the room price just because it was 2 days before the eclipse." - "Let's do it again." - "My stay was pleasant, nice and quiet. No problems" - "Mediocre"

Super 8 by Wyndham Sikeston/Miner Area
Hotel
2609 E Malone Ave, Sikeston, MO, 63801, USA

Hotel in Sikeston with free breakfast and a 24-hour front desk
This hotel features a 24-hour front desk, a library, and RV/bus/truck parking. Free on-the-go breakfast and free WiFi in public areas are also provided. Other amenities include a vending machine.
Change of towels is available on request.
Super 8 by Wyndham Sikeston/Miner Area offers 60 air-conditioned accommodations with hair dryers and blackout drapes/curtains. Premium cable television is provided. Rooms have partially open bathrooms. Bathrooms include shower/tub combinations.

This Sikeston hotel provides complimentary wireless Internet access. Business-friendly amenities include desks along with free local calls (restrictions may apply). Change of towels and change of bedsheets can be requested. Housekeeping is provided daily.

Guest Reviews:

- "good place to stay" - "Nice quiet place no noise " - "Good " - "Good place, quiet. Breakfast not the greatest but still ok pleanty of places to walk to for food and convenience " - "Awesome hotel and love the kitchenettes in the rooms and the heated pool and hot tub! Wonderful place to stay!" - "Love the fact they had smoking rooms the bed was not the most comfortable but for the price " - "The start was excellent, quite, comfortable. I enjoyed myself and my friend also. "

Super 8 by Wyndham Charleston Sikeston East MO
Hotel
310 South Story Street, Charleston, MO, MO 63834, USA

Offering a seasonal outdoor pool, this motel serves a daily grab and go breakfast and offers rooms with free Wi-Fi. Columbus-Belmont State Park is 16 mi away. A flat-screen cable TV is provided in each air-conditioned room at Super 8 Charleston. Complete with a microwave, the dining area also has a refrigerator and a coffee machine. Private bathrooms also come with a bath or shower. A 24-hour reception greets guests of Super 8 Charleston. A business center with fax and photocopying services is available. Towosahgy State Historic Site and Big Oak Tree State Park are within 24 mi away from Charleston Super 8. Barkley Regional Airport is 32 mi away. Free parking for cars, trucks and busses is available.

Guest Reviews:

- "Clean. Good location. Met our limited budget needs." - "Good room for a quick family visit" - "comfterble" - "Stayed for 2 nights - good base location to go to either southern Illinois or Missouri to view the eclipse. We really l" - "OK if you really need a bed for the night." - "We slept good. Bed was OK" - "A good place to stay if you're ok with just OK" - "A decent place to stay but with on-duty personnel worth going somewhere else."

Quality Inn Charleston - Sikeston
Hotel
102 Drake St, Charleston, MO, 63834, USA

Hotel in Charleston with free breakfast and a 24-hour front desk
A business center, a 24-hour front desk, and RV/bus/truck parking are available at this hotel. Free buffet breakfast and free WiFi in public areas are also provided. Other amenities include a front-desk safe and a vending machine.
Quality Inn Charleston - Sikeston offers 40 accommodations, which are accessible via exterior corridors and feature coffee/tea makers and hair dryers. Accommodations offer separate sitting areas. 32-inch LCD televisions come with premium cable channels. Rooms have partially open bathrooms. Bathrooms include shower/tub combinations.

This Charleston hotel provides complimentary wired and wireless Internet access. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Additionally, rooms include irons/ironing boards and blackout drapes/curtains. Housekeeping is provided daily.

Guest Reviews:

- "Everything was very nice it was a quick pit.stop on a long trip but was clean and they upgraded our room at no extra charge when we got there" - "Very nice " - "Good " - "It was a nice and friendly place and a queen" - "Great bed. " - "With my previous experience as a housekeeper at a hotel and knowing what areas to clean. I can say that the areas beyond the eye was not clean, the mirrors was dirty and they didn’t not offer complimentary breakfast or late check out. "

Country Yard Inn Sikeston - Miner Exit 67 on I-55
Hotel
110 South Interstate Drive, Sikeston, MO, MO 63801, USA

Country Yard Inn Sikeston - Miner Exit 67 on I-55 is offering accommodations in Sikeston. The 2-star hotel has air-conditioned rooms with a private bathroom and free WiFi. At the hotel, the rooms include a desk and a flat-screen TV. All rooms will provide guests with a microwave. The reception at Country Yard Inn Sikeston - Miner Exit 67 on I-55 can provide tips on the area. Cape Girardeau Regional Airport is 27 miles from the property.

Guest Reviews:

- "Just Wonderful and pleasant place to relax" - "Clean and nice property"

Comfort Inn & Suites Sikeston I-55
Hotel
109 Matthews Ln, Sikeston, MO, 63801, USA

Hotel in Sikeston with a fitness center and a 24-hour front desk
This hotel features an indoor pool, a fitness center, and a business center. Free WiFi in public areas and free self parking are also provided. Other amenities include laundry facilities, a 24-hour front desk, and a front-desk safe.
Comfort Inn & Suites Sikeston I-55 offers 64 air-conditioned accommodations with coffee/tea makers. Guests can surf the web using the complimentary wireless Internet access.

Bathrooms include bathtubs or showers. Business-friendly amenities include desks and phones.


Recreational amenities at the hotel include an indoor pool and a fitness center.

Guest Reviews:

- "We stayed here the week before this, but this time it was much better. The man at the front desk was very helpful. Still had the same issue with the TV and remote. You should consider a simple one page set of directions for their operation to save your staff time and effort fixing everyone's TV!" - "It was a nice location off of i55. Lots of fast food. Overall clean. No issues. " - "The best value for money I have ever had. Exceptional service and cleanliness. My room was fantastic. Huge and spotless. Theres an elevator and they are pet friendly. I travel a great deal and this was the best. Good breakfast with lots of choices, including healthy choices. Safe area right next to a McDonalds and a Burger King, but not 24hr ones so it was quiet at night. "

Quality Inn Cairo I-57
Hotel
13201 Kessler Road Route 3 and I-57, Cairo, IL, IL 62914, USA

Stay near the banks of the Ohio and Mississippi rivers at the Quality Inn hotel in Cairo, Illinois. The hotel's location off Interstate 57 provides convenient access to Fort Defiance State Park, Wickliffe Mounds State Park, Magnolia Manor, Birds Blue Hole and Cypress Creek National Wildlife Refuge. At the hotel, you’ll appreciate features and amenities that include free wireless high-speed Internet access, free hot breakfast and coffee, free local calls, seasonal outdoor pool and pet-friendly hotel; fees apply. Take care of business on the go with our copy and fax services, or enjoy the scenery at our outdoor picnic area. Guest rooms are spacious and feature amenities such as microwaves, refrigerators, hair dryers, expanded cable television with HBO. The proximity to the neighboring states of Missouri and Kentucky provide even more to see and do. Explore Cairo’s historic district, where you’ll find the Old Custom House, a former post office and courthouse that now serves as a museum. Several shops and restaurants are also close by.

Guest Reviews:

- "Would certainly stay there again if in the area" - "Don't hesitate to stay here." - "On the whole, I’d rather be somewhere else." - "Old hotel with decent accommodations" - "You should rather drive an hour to someplace else" - "Not good trouble with entry card bathroom dirty wont book again"

Quality Inn Cairo I-57
Hotel
13201 Kessler Road, Cairo, IL, 62914, USA

Hotel in Cairo with free breakfast and a 24-hour front desk
This hotel features coffee/tea in a common area, a 24-hour front desk, and free newspapers. Free full breakfast, free WiFi in public areas, and free self parking are also provided. Other amenities include a picnic area and RV/bus/truck parking.
Quality Inn Cairo I-57 offers 38 air-conditioned accommodations with coffee/tea makers and complimentary weekday newspapers. Flat-screen televisions come with cable channels. Refrigerators and microwaves are provided. Bathrooms include complimentary toiletries and hair dryers.

This Cairo hotel provides complimentary wireless Internet access. Business-friendly amenities include phones along with free local calls (restrictions may apply). Housekeeping is provided daily.

Guest Reviews:

- "Great breakfast, coffee in room, walk to Wall carpeting. " - "The room was very clean and the breakfast was pretty good. No complaints" - "The main entrances to the hotel building were open and wouldn't lock. The gentleman at the desk was pleasant and helpful, giving us a great recommendation for a restaurant a few miles away on route 57. The breakfast was good and the dining area appeared newly remodeled and decorated. However, the TV channels were sporadic in its clarity. "

Quality Inn Charleston - Sikeston
Hotel
102 Drake Street, Charleston, MO, MO 63834, USA

Located in Charleston, Quality Inn Charleston - Sikeston has air-conditioned rooms with free WiFi. Ballard Wildlife Management Area is 24 miles from the inn. Buffet and continental breakfast options are available each morning at the inn. Free private parking and a business center are available, as well as a 24-hour front desk. Cape Girardeau Regional Airport is 38 miles from the property.

Guest Reviews:

- "Nice for 1 night" - "Pleasant and acceptable for the price." - "It was OK"

Country Yard Inn and Suite
Hotel
110 South Interstate Drive, Sikeston, MO, 63801, USA

Motel in Sikeston with free parking
A 24-hour front desk, free self parking, and free WiFi in public areas are available at this motel.
Housekeeping is available on request.
Country Yard Inn and Suite offers 35 accommodations with hair dryers. Televisions come with cable channels. Bathrooms include showers with rainfall showerheads.

This Sikeston motel provides complimentary wireless Internet access. Business-friendly amenities include phones along with free local calls (restrictions may apply). Housekeeping is offered on request and irons/ironing boards can be requested.

Guest Reviews:

- " Cleanliness and Quality " - "The receptionist told me upon walking in the door that their television service was not functioning. Asked for a refund and he told me to contact Expedia which very smoothly." - "Spacious room and ery clean and updated. Very impressed." - "The staff was very friendly and professional. The new management is taking very good care of their customers and making it a comfortable place to stay. The room itself and bathroom was very clean. It is very quite and convenient to near by restaurants. The coffee in room was great. I will return next time when i go through this route, I highly recommended this place!!"

Charleston Eagle Inn
Hotel
2811 East Marshall Street, Charleston, MO, MO 63834

Featuring free Wi-Fi throughout the property and in every guest room, this Charleston, Missouri motel is 1 mile away from Interstate 57. Each room includes a flat-screen cable TV, microwave, refrigerator and coffeemaker at Charleston Eagle Inn. The private bathroom is equipped with a hairdryer for additional convenience. Free parking is available on site at Eagle Inn Charleston. Guests can enjoy access to the fitness center next door or make use of the fax and photocopying services in the front office. The Mississippi River is 10 miles northwest of this motel. The Sikeston Memorial Municipal Airport can be reached in 20 minutes’ drive.

Guest Reviews:

- "Relaxing room's"

Eagle Inn Charleston
Hotel
2811 East Marshall Street, Charleston, MO, 63834, USA

Motel in Charleston with a health club and a 24-hour front desk
Along with a health club, this motel has a 24-hour front desk and free self parking. WiFi in public areas is free. Other amenities include a vending machine.
Eagle Inn Charleston offers 19 accommodations with coffee/tea makers and hair dryers. Televisions come with premium cable channels. Guests can make use of the in-room refrigerators and microwaves.

Guests can surf the web using the complimentary wireless Internet access. Business-friendly amenities include desks along with free local calls (restrictions may apply). Housekeeping is provided daily.


Recreational amenities at the motel include a health club.

Guest Reviews:

- "Comfortable bed, easy access to room" - "Ok" - "I saw a lot of bad reviews about eagle inn, but when i got there, the service was polite, room was clean, towels were normal hotel towels. Bed was comfy no bugs, was it a bit dated? Yes but for 80 bucks a night, its not gonna be the ritz carlton. All in all, good pleasant experience" - "Nice little place. The beds are very comfortable. Plenty of space. " - "Room was clean and manager was friendly. Did not see any 🐜. "

Lambert’s Homestead. Very Cozy & Clean 5 bed home.
House
Sikeston, Missouri, USA

Welcome to Sikeston! Stay in our home only 0.75 miles from the interstate and 0.5 miles from your infamous Lambert's Cafe: Home of the THROWN ROLLS! During your stay enjoy a fun game of pool in our pool lounge! This cozy home is tucked back into a quiet neighborhood where you can enjoy a nice walk in the evenings and enjoy the back yard during your stay as you enjoy the sunset in the evenings that you'll never forget in beautiful Sikeston, Missouri.

The space
***Deep cleaned property. Extremely clean and safe.

VERY spacious private 3 bedroom home. There are 3 bedrooms, all with queen beds, as well as a queen sleeper, as well as a comfy blowup queen bed. Enjoy the large back yard!

Guest access
Guests will have a keyless entry system that they will use to enter the property. A code will be provided to them via email upon booking.

Guest Reviews:

- "We enjoyed our stay. The property was exactly as advertised. We'll definitely be looking to use this property next year if it's still available." - "In town for a family funeral. Arrived at wrong address due to VRBO listing, but property was actually 213 Kinder. Parker was very responsive and we got to the right property in a few minutes. A bottle of wine welcomed us when we got inside. The living and dining room are open and the space is good for hanging out. The beds were comfortable and the two full baths were clean. Shampoo, conditioner, soap, and body lotion were provided. Great deal for Sikeston, close to the interstate and Lambert’s."

Tiny Home with Huge Outdoor Space
Cabin
East Prairie, Missouri, USA

New tiny home with huge outdoor space, private parking , RV hookup in a safe neighborhood. Close to lots of fishing & hunting . Small quite town with friendly local people and local restaurants very close by

Amenities:

Balcony/Terrace • Kitchen • Laundry • Bedding/Linens • Child Friendly • Child Friendly • Air Conditioner

Charleston Vacation-Rentals on the Map

Compare the Best Vacation-Rentals in Charleston – Addresses, Prices, Stars, Rating, and Review Count

Property Name Address Price ($) Star Rating Review Count Book
Travel Inn and Suites- Sikeston Miner I-55 exit-67 100 Matthews Lane, Sikeston, MO, MO 63801 70 4.0 8.0 561 Click here
Drury Inn & Suites Sikeston, MO 2608 East Malone Ave, Miner, Sikeston, MO, 63801, USA 110 3.0 9.4 1005 Click here
Drury Inn & Suites Sikeston 2608 East Malone Avenue, Sikeston, MO, MO 63801, USA 131 3.0 9.3 707 Click here
Best Western Plus Sikeston 120 S Interstate Drive, Sikeston, MO, 63801, USA 95 2.0 8.4 1003 Click here
Best Western Plus Sikeston 120 South Interstate Drive, Sikeston, MO, MO 63801, USA 94 3.0 7.5 325 Click here
Pear Tree Inn Sikeston 2602 E Malone Avenue, Sikeston, MO, 63801, USA 88 2.0 9.4 1002 Click here
Comfort Inn & Suites Sikeston I-55 109 Matthews Lane, Sikeston, MO, MO 63801, USA 108 3.0 8.3 204 Click here
Days Inn and Suites by Wyndham Sikeston 220 S Interstate Dr, Sikeston, MO, 63801, USA 71 2.0 7.2 1001 Click here
Super 8 by Wyndham Sikeston/Miner Area 2609 East Malone Avenue, Sikeston, MO, MO 63801, USA 60 3.0 6.6 131 Click here
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67) 100 Matthews Lane, Sikeston, MO, 63801, USA 67 2.0 8.4 708 Click here
Pear Tree Inn Sikeston 2602 East Malone Avenue, Sikeston, MO, MO 63801, USA 112 2.0 9.1 832 Click here
Super 8 by Wyndham Charleston/Sikeston East MO 310 S Story St, Charleston, MO, 63834, USA 62 2.0 6.6 607 Click here
Days Inn and Suites by Wyndham Sikeston 220 South Interstate Dr, Sikeston, MO, 63801, USA 72 2.0 7.7 308 Click here
Super 8 by Wyndham Sikeston/Miner Area 2609 E Malone Ave, Sikeston, MO, 63801, USA 71 2.0 6.6 559 Click here
Super 8 by Wyndham Charleston Sikeston East MO 310 South Story Street, Charleston, MO, MO 63834, USA 69 2.0 5.0 201 Click here
Quality Inn Charleston - Sikeston 102 Drake St, Charleston, MO, 63834, USA 72 2.0 6.8 406 Click here
Country Yard Inn Sikeston - Miner Exit 67 on I-55 110 South Interstate Drive, Sikeston, MO, MO 63801, USA 68 2.0 5.0 86 Click here
Comfort Inn & Suites Sikeston I-55 109 Matthews Ln, Sikeston, MO, 63801, USA 95 2.0 8.4 277 Click here
Quality Inn Cairo I-57 13201 Kessler Road Route 3 and I-57, Cairo, IL, IL 62914, USA 67 2.0 4.8 73 Click here
Quality Inn Cairo I-57 13201 Kessler Road, Cairo, IL, 62914, USA 76 2.0 6.6 272 Click here
Quality Inn Charleston - Sikeston 102 Drake Street, Charleston, MO, MO 63834, USA 68 2.0 5.3 58 Click here
Country Yard Inn and Suite 110 South Interstate Drive, Sikeston, MO, 63801, USA 63 2.0 6.8 116 Click here
Charleston Eagle Inn 2811 East Marshall Street, Charleston, MO, MO 63834 549 1.0 4.8 14 Click here
Eagle Inn Charleston 2811 East Marshall Street, Charleston, MO, 63834, USA 73 2.0 6.8 100 Click here
Lambert’s Homestead. Very Cozy & Clean 5 bed home. Sikeston, Missouri, USA 109 4.65 26 Click here
Tiny Home with Huge Outdoor Space East Prairie, Missouri, USA 89 1 Click here

Note: The prices for each Vacation-Rentals in Charleston do vary. This can be because of the number of people you are booking for, how far in advance you book and the season. The prices above are only meant as a rough estimate for comparison purposes. Click the buttons above (or click here) to get the latest prices.

Frequently Asked Questions

Vacation rentals in Charleston that include a pool include:

  • Drury Inn & Suites Sikeston, MO.- Review Count: 1005, Rating: 9.4
  • Drury Inn & Suites Sikeston.- Review Count: 707, Rating: 9.3
  • Best Western Plus Sikeston.- Review Count: 1003, Rating: 8.4

Family-friendly vacation rentals in Charleston include:

  • Travel Inn and Suites- Sikeston Miner I-55 exit-67.- Review Count: 561, Rating: 8.0
  • Drury Inn & Suites Sikeston, MO.- Review Count: 1005, Rating: 9.4
  • Drury Inn & Suites Sikeston.- Review Count: 707, Rating: 9.3

Pet-friendly vacation rentals in Charleston include:

  • Travel Inn and Suites- Sikeston Miner I-55 exit-67.- Review Count: 561, Rating: 8.0
  • Best Western Plus Sikeston.- Review Count: 325, Rating: 7.5
  • Comfort Inn & Suites Sikeston I-55.- Review Count: 204, Rating: 8.3

Vacation rentals in Charleston that include breakfast options include:

  • Drury Inn & Suites Sikeston, MO.- Review Count: 1005, Rating: 9.4
  • Best Western Plus Sikeston.- Review Count: 1003, Rating: 8.4
  • Best Western Plus Sikeston.- Review Count: 325, Rating: 7.5

Vacation rentals in Charleston with private or on-site parking include:

  • Travel Inn and Suites- Sikeston Miner I-55 exit-67.- Review Count: 561, Rating: 8.0
  • Drury Inn & Suites Sikeston, MO.- Review Count: 1005, Rating: 9.4
  • Drury Inn & Suites Sikeston.- Review Count: 707, Rating: 9.3

Some of the best Vacation Rentals in Charleston are:

  • Travel Inn and Suites- Sikeston Miner I-55 exit-67.- Review Count: 561, Rating: 8.0
  • Drury Inn & Suites Sikeston, MO.- Review Count: 1005, Rating: 9.4
  • Drury Inn & Suites Sikeston.- Review Count: 707, Rating: 9.3

Some of the popular Vacation Rentals in Charleston are:

  • Drury Inn & Suites Sikeston, MO.- Review Count: 1005, Rating: 9.4
  • Best Western Plus Sikeston.- Review Count: 1003, Rating: 8.4
  • Pear Tree Inn Sikeston.- Review Count: 1002, Rating: 9.4